Description

(4-Cyclobutoxypyridin-2-Yl)Methanamine is a high-purity organic building block featuring a pyridine core substituted with a cyclobutoxy group and an aminomethyl moiety. This specific molecular architecture makes it a valuable intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a building block for creating novel pesticides, herbicides, or fungicides with potentially improved efficacy and environmental profiles.
• Ligand and Catalyst Development: The pyridine and amine functional groups make it suitable for designing novel ligands for metal catalysis or organocatalysts used in asymmetric synthesis.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, or organic electronic materials due to its aromatic and modifiable structure.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	(4-Cyclobutoxypyridin-2-Yl)Methanamine
CAS No.	1250948-64-1
Molecular Formula	C10H14N2O
Molecular Weight	178.23 g/mol
Synonyms	2-(Aminomethyl)-4-cyclobutoxypyridine; 1-(4-Cyclobutoxypyridin-2-yl)methanamine; 4-Cyclobutoxy-2-pyridinemethanamine; (4-Cyclobutoxy-2-pyridinyl)methanamine; 2-Pyridinemethanamine, 4-cyclobutoxy-; (4-Cyclobutoxypyridin-2-yl)methylamine
EINECS	Contact for details

Quality Control

Our (4-Cyclobutoxypyridin-2-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.