Description

6-Cyclobutoxypyridine-2-Carboxylic Acid CAS NO 1250298-25-9 is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine-carboxylic acid scaffold substituted with a cyclobutoxy moiety. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in areas requiring complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process chemistry for constructing the core structure of potential APIs.
• Chemical Biology & Proteomics: Employed as a specialized scaffold or linker in the design of chemical probes for studying biological pathways and protein function.
• Agrochemical Research: Acts as an intermediate in the development of new generation herbicides and pesticides with improved efficacy.
• Material Science: Investigated for use in creating functionalized ligands for metal-organic frameworks (MOFs) or catalysts.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	6-Cyclobutoxypyridine-2-Carboxylic Acid
CAS No.	1250298-25-9
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	2-Pyridinecarboxylic acid, 6-cyclobutoxy-; 6-Cyclobutoxy-2-pyridinecarboxylic acid; 6-Cyclobutoxypicolinic Acid; 2-Carboxy-6-cyclobutoxypyridine; Cyclobutyl 6-carboxypyridin-2-yl ether; Picolinic acid, 6-cyclobutoxy-; 1250298-25-9; 6-Cyclobutoxy-pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Cyclobutoxypyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.