Description

Spiro[Cyclopropane-2,1-Indane]-1-Carboxylic Acid CAS NO 1250150-08-3 is a high-purity, synthetically valuable spirocyclic carboxylic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing new-generation pesticides and herbicides with spirocyclic motifs for enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Academic & R&D: A valuable tool compound for methodological studies in organic chemistry, including cyclopropanation and spiroannulation reactions.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Spiro[Cyclopropane-2,1-Indane]-1-Carboxylic Acid
CAS No.	1250150-08-3
Molecular Formula	C12H12O2
Molecular Weight	188.22 g/mol
Synonyms	1H-Indene-1-carboxylic acid, 2,3-dihydro-2-spirocyclopropane-; 2,3-Dihydro-2-spirocyclopropane-1H-indene-1-carboxylic acid; Spiro[cyclopropane-1,2'-indene]-1'-carboxylic acid; 1'-Carboxyspiro[cyclopropane-1,2'-indene]; Spiro(cyclopropane-2,1'-indene)-1'-carboxylic acid; 1250150-08-3; Spirocyclopropaneindanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopropane-2,1-Indane]-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for your grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.