Description

5-Bromo-2-Chloro-3-(Pyrrolidine-1-Carbonyl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a halogenated pyridine core. This compound is specifically engineered for use in medicinal chemistry and drug discovery programs, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies developing targeted therapies, particularly in oncology and central nervous system (CNS) drug research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of small molecule drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its halogenated, functionalized pyridine structure.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel pesticides and herbicides.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university laboratories for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	5-Bromo-2-Chloro-3-(Pyrrolidine-1-Carbonyl)Pyridine
CAS No.	1249608-32-9
Molecular Formula	C11H10BrClN2O
Molecular Weight	301.57 g/mol
Synonyms	5-Bromo-2-chloro-3-(pyrrolidine-1-carbonyl)pyridine; 2-Chloro-5-bromo-3-(1-pyrrolidinylcarbonyl)pyridine; 3-(Pyrrolidine-1-carbonyl)-5-bromo-2-chloropyridine; 5-Bromo-2-chloro-3-pyrrolidin-1-ylcarbonylpyridine; 1249608-32-9; 5-Br-2-Cl-3-(Pyrrolidine-1-Carbonyl)Pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-3-(Pyrrolidine-1-Carbonyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.