Description

Ethyl 2-(3,5-Dimethylphenyl)-2,2-Difluoroacetate is a high-value fluorinated organic building block. This compound is significant for its role in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of difluoroacetate groups is crucial for modulating biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in fine chemical and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoromethyl group enhances lipophilicity and systemic activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Fluorine Chemistry Research: An essential reagent for academic and industrial laboratories exploring new C-F bond formation reactions and fluorination methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke fine chemicals on a commercial scale.

Basic Information

Product Name	Ethyl 2-(3,5-Dimethylphenyl)-2,2-Difluoroacetate
CAS No.	1248927-78-7
Molecular Formula	C12H14F2O2
Molecular Weight	228.24 g/mol
Synonyms	Ethyl 3,5-Dimethyl-α,α-difluorobenzeneacetate; 2-(3,5-Dimethylphenyl)-2,2-difluoroacetic Acid Ethyl Ester; Ethyl 2,2-Difluoro-2-(3,5-dimethylphenyl)acetate; α,α-Difluoro-3,5-dimethylbenzeneacetic Acid Ethyl Ester; DFEA; Ethyl Difluoro(3,5-dimethylphenyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3,5-Dimethylphenyl)-2,2-Difluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.