Description

2-Cyclopropyl-2-Hydroxy-Propionic Acid Methyl Ester is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyclopropyl ring and a hydroxy ester moiety, makes it a valuable precursor for constructing complex molecules with specific stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex flavors, fragrances, and advanced materials.
• Academic & Institutional Research: Serves as a standard or starting material in methodological studies and synthetic chemistry research.

Basic Information

Product Name	2-Cyclopropyl-2-Hydroxy-Propionic Acid Methyl Ester
CAS No.	1248911-98-9
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Methyl 2-cyclopropyl-2-hydroxypropanoate; Methyl 2-hydroxy-2-cyclopropylpropanoate; 2-Hydroxy-2-cyclopropylpropanoic acid methyl ester; α-Hydroxy-α-cyclopropylpropionic acid methyl ester; (RS)-Methyl 2-cyclopropyl-2-hydroxypropionate; 2-Cyclopropyl-2-hydroxypropionic acid methyl ester; Cyclopropanecarboxylic acid, 1-hydroxy-1-methylethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopropyl-2-Hydroxy-Propionic Acid Methyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications, which typically include identity confirmation, assay, chiral purity, and control of key impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.