Description

N2-Cyclobutylpyridine-2,4-Diamine CAS NO 1248791-40-3 is a high-purity, advanced pharmaceutical intermediate featuring a cyclobutyl-substituted pyridinediamine core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, antiviral, and central nervous system (CNS) applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures, particularly in kinase inhibitor programs.
• Chemical Research & Development: Serves as a standard or reagent in method development and structure-activity relationship (SAR) studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for exploratory chemistry and novel reaction pathway investigations.

Basic Information

Product Name	N2-Cyclobutylpyridine-2,4-Diamine
CAS No.	1248791-40-3
Molecular Formula	C9H13N3
Molecular Weight	163.22 g/mol
Synonyms	2,4-Pyridinediamine, N2-cyclobutyl-; N2-Cyclobutyl-2,4-pyridinediamine; N-(Cyclobutyl)pyridine-2,4-diamine; 2,4-Diamino-N-cyclobutylpyridine; 1248791-40-3; Cyclobutyl-pyridine-2,4-diamine; N-Cyclobutylpyridine-2,4-diamine
EINECS	Contact for details

Quality Control

Our N2-Cyclobutylpyridine-2,4-Diamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.