Description

1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-2-One is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine and sulfonyl pyrrolidinone scaffold. This compound is valued for its role as a key building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Protease Inhibitor Development: Used in the research and development of inhibitors targeting specific enzymes, such as kinases or proteases.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological processes and target validation.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-2-One
CAS No.	1247840-97-6
Molecular Formula	C9H9BrN2O3S
Molecular Weight	305.15 g/mol
Synonyms	1-[(5-Bromo-3-pyridinyl)sulfonyl]-2-pyrrolidinone; 2-Pyrrolidinone, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 1-(5-Bromopyridine-3-sulfonyl)pyrrolidin-2-one; 5-Bromo-3-(2-oxopyrrolidin-1-ylsulfonyl)pyridine; 1-(5-Bromo-3-pyridylsulfonyl)pyrrolidin-2-one
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.