Description

Methyl 5-Fluoro-2-Phenylbenzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and other specialty chemicals where the introduction of a fluorine atom and a benzoate ester moiety is critical.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic materials, contributing to improved performance in display technologies.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions, esterification studies, and as a model substrate for methodological development in academic and industrial laboratories.
• Fine Chemical Production: Integral to the multi-step synthesis of complex dyes, flavors, and fragrances that require specific fluorinated aromatic structures.

Basic Information

Product Name	Methyl 5-Fluoro-2-Phenylbenzoate
CAS No.	1247810-91-8
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	5-Fluoro-2-phenylbenzoic acid methyl ester; Methyl 5-fluoro-2-phenylbenzoate; Methyl 5-fluoro-[1,1'-biphenyl]-2-carboxylate; 2-Phenyl-5-fluorobenzoic acid methyl ester; 5-Fluoro-2-biphenylcarboxylic acid methyl ester; Benzoic acid, 5-fluoro-2-phenyl-, methyl ester; [1,1'-Biphenyl]-2-carboxylic acid, 5-fluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluoro-2-Phenylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.