Description

6-Bromo-2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, active ingredient synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and boronate functionality.
• Material Science Research: Employed as a building block for creating organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and imaging agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects requiring specific halogenated pyridine boronic esters.
• Academic & Industrial R&D: A staple reagent in laboratory settings for methodological development and exploring new synthetic pathways.

Basic Information

Item	Detail
Product Name	6-Bromo-2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1247726-85-7
Molecular Formula	C11H14BBrClNO2
Molecular Weight	318.40 g/mol
Synonyms	2-Chloro-6-bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Bromo-6-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-Bromo-2-chloropyridine-3-boronic acid pinacol ester; (6-Bromo-2-chloropyridin-3-yl)boronic acid pinacol ester; 1247726-85-7; Pyridine, 6-bromo-2-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured and tested under a strict quality management system. We guarantee high purity and consistency, with specifications typically meeting or exceeding 98.0% (HPLC) purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.