Description

2-Cyclobutoxypyridine-4-Carboxylic Acid is a high-purity, functionalized pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a cyclobutyl ether moiety, makes it a versatile intermediate for constructing complex molecular architectures with specific steric and electronic properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridine core and functional groups contribute to biological activity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials and liquid crystals due to its conjugated system and potential for derivatization.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tools to study biological processes and enzyme functions.

Basic Information

Product Name	2-Cyclobutoxypyridine-4-Carboxylic Acid
CAS No.	1247662-13-0
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2-cyclobutoxy-; 2-Cyclobutoxyisonicotinic Acid; 2-(Cyclobutoxy)pyridine-4-carboxylic acid; 4-Carboxy-2-cyclobutoxypyridine; Isonicotinic acid, 2-cyclobutoxy- derivative; 1247662-13-0; 2-Cyclobutoxy-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 2-Cyclobutoxypyridine-4-Carboxylic Acid is produced and analyzed under current Good Manufacturing Practice (cGMP) principles for non-API starting materials. Identity, purity, and impurity profiles are verified using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.