Description

6-Oxo-1-(2,2,2-Trifluoroethyl)-1,6-Dihydropyridine-3-Carboxylic Acid is a high-value, fluorinated pyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a trifluoroethyl group and a carboxylic acid moiety, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of new drug candidates, particularly for developing molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, leveraging the fluorine atoms for improved efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential building block for specialty polymers or functional materials requiring fluorinated components.
• Ligand and Catalyst Development: The carboxylic acid and heterocyclic core can be utilized to develop novel chelating ligands or organocatalysts.

Basic Information

Product Name	6-Oxo-1-(2,2,2-Trifluoroethyl)-1,6-Dihydropyridine-3-Carboxylic Acid
CAS No.	1247612-70-9
Molecular Formula	C8H6F3NO3
Molecular Weight	221.13 g/mol
Synonyms	1-(2,2,2-Trifluoroethyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 1,6-dihydro-1-(2,2,2-trifluoroethyl)-6-oxo-; 6-Hydroxy-1-(2,2,2-trifluoroethyl)-3-pyridinecarboxylic acid; 1-(Trifluoroethyl)-6-oxo-1,6-dihydronicotinic acid; 6-Oxo-1-(trifluoroethyl)-1,6-dihydropyridine-3-carboxylic acid; 1247612-70-9 (CAS); TFEPCA (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 6-Oxo-1-(2,2,2-Trifluoroethyl)-1,6-Dihydropyridine-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and process development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.