Description

5,8,11-Trioxa-2-Azatridecanoic Acid, 13-[[(4-Methylphenyl)Sulfonyl]Oxy]-, 1,1-Dimethylethyl Ester is a specialized organic compound featuring a unique polyether-azatridecanoic acid backbone with a tosylate-protected terminal hydroxyl group. This molecular architecture makes it a valuable protected intermediate and building block in advanced synthetic chemistry. It is primarily sought after by R&D and process development teams in the pharmaceutical and fine chemical industries for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic & Linker Chemistry: Used in the design and synthesis of peptidomimetics, prodrugs, and bioconjugates due to its polyether spacer and protected functional groups.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating specialized polymers with tailored properties.
• Ligand & Catalyst Development: Employed as a precursor for synthesizing chelating ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Utilized in the development of molecular probes, tags, and tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5,8,11-Trioxa-2-Azatridecanoic Acid, 13-[[(4-Methylphenyl)Sulfonyl]Oxy]-, 1,1-Dimethylethyl Ester
CAS No.	1246999-33-6
Molecular Formula	C23H37NO8S
Molecular Weight	487.61 g/mol
Synonyms	tert-Butyl 13-[(4-methylphenyl)sulfonyl]oxy-5,8,11-trioxa-2-azatridecanoate; 2-[2-[2-[2-(tert-Butoxy)-2-oxoethoxy]ethoxy]ethoxy]-N-(2-{[4-methylphenyl)sulfonyl]oxy}ethyl)acetamide; PEG3-OTs tert-Butyl Ester; Tetraethylene Glycol Monotosylate tert-Butyl Ester Amide; Boc-PEG3-OTs (common abbreviation); 13-(p-Toluenesulfonyloxy)-5,8,11-trioxa-2-azatridecanoic Acid tert-Butyl Ester; N-(2-{2-[2-(2-{[(tert-Butoxy)carbonyl]amino}ethoxy)ethoxy]ethoxy}ethyl)-4-methylbenzenesulfonamide Derivative
EINECS	Contact for details

Quality Control

Our production of 5,8,11-Trioxa-2-Azatridecanoic Acid, 13-[[(4-Methylphenyl)Sulfonyl]Oxy]-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analysis including HPLC for purity and identity confirmation via NMR and MS. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Assay	≥ 90.0% (by weight)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.