Description

(E)-2-Bromo-6-(3-(pyrrolidin-1-yl)-1-methyl-1H-indazol-5-yl)pyridine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in modern drug discovery programs. It is primarily needed by pharmaceutical companies, biotechnology research firms, and contract development and manufacturing organizations (CDMOs) working on innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or tagged molecules for biological target identification and validation studies.

Basic Information

Product Name	(E)-2-Bromo-6-(3-(pyrrolidin-1-yl)-1-methyl-1H-indazol-5-yl)pyridine
CAS No.	1246857-70-4
Molecular Formula	C18H19BrN4
Molecular Weight	371.28 g/mol
Synonyms	(E)-2-Bromo-6-[3-(1-pyrrolidinyl)-1-methyl-1H-indazol-5-yl]pyridine; 2-Bromo-6-((E)-3-(pyrrolidin-1-yl)-1-methyl-1H-indazol-5-yl)pyridine; (E)-2-Bromo-6-(3-(pyrrolidin-1-yl)-1-methyl-1H-indazol-5-yl)pyridine; 1246857-70-4; (E)-2-Bromo-6-(3-(pyrrolidin-1-yl)-1-methylindazol-5-yl)pyridine
EINECS	Contact for details

Quality Control

Our (E)-2-Bromo-6-(3-(pyrrolidin-1-yl)-1-methyl-1H-indazol-5-yl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.