Description

5-(tert-Butyldimethylsilyl)Oxy-2-Mercaptobenzimidazole is a sophisticated, organosilicon-protected derivative of the benzimidazole pharmacophore, designed for advanced synthetic chemistry. This compound matters as a critical, high-purity building block, enabling the precise construction of complex molecules where selective deprotection and functionalization are required. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of novel drug candidates, particularly those targeting various enzyme systems.
• Agrochemical Research: Used in developing new fungicides, herbicides, and plant growth regulators that leverage the benzimidazole core structure.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the development of specialty chemicals, ligands for catalysis, or advanced organic materials.

Basic Information

Product Name	5-(tert-Butyldimethylsilyl)Oxy-2-Mercaptobenzimidazole
CAS No.	1246814-75-4
Molecular Formula	C₁₃H₂₀N₂OSSi
Molecular Weight	280.46 g/mol
Synonyms	5-[(tert-Butyldimethylsilyl)oxy]-1H-benzimidazole-2-thiol; 2-Mercapto-5-[(tert-butyldimethylsilyl)oxy]-1H-benzimidazole; 5-(TBDMSO)-2-mercaptobenzimidazole; 5-(tert-Butyldimethylsiloxy)-2-mercaptobenzimidazole; 2-Thiol-5-O-TBDMS-benzimidazole; 5-Hydroxy-2-mercaptobenzimidazole TBDMS ether; BTA-TBDMS; CAS 1246814-75-4
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyldimethylsilyl)Oxy-2-Mercaptobenzimidazole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.