Description

tert-Butyl 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine-7-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system and anti-infective therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially those containing the [1,2,4]triazolo[4,3-a]pyridine scaffold.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial labs for exploring new chemical entities and reaction pathways.
• Material Science: Potential application in the synthesis of specialty chemicals and functional materials requiring complex nitrogen-containing heterocycles.

Basic Information

Product Name	tert-Butyl 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine-7-carboxylate
CAS No.	1246759-50-1
Molecular Formula	C11H12ClN3O2
Molecular Weight	253.69 g/mol
Synonyms	5-Chloro-7-[(1,1-dimethylethoxy)carbonyl][1,2,4]triazolo[4,3-a]pyridine; tert-Butyl 5-chloro[1,2,4]triazolo[4,3-a]pyridine-7-carboxylate; 1246759-50-1; 5-Chloro-7-(tert-butoxycarbonyl)[1,2,4]triazolo[4,3-a]pyridine; 7-(tert-Butoxycarbonyl)-5-chloro[1,2,4]triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine-7-carboxylate adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.