Description

(3R,4S,5R)-Butyl 3,4,5-Trihydroxycyclohex-1-Enecarboxylate is a high-purity, stereochemically defined cyclohexene derivative that serves as a critical chiral building block and synthetic intermediate. Its precise stereochemistry and functional group array make it a valuable scaffold for constructing complex molecules with defined three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly for developing active pharmaceutical ingredients (APIs), advanced agrochemicals, and novel materials where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing advanced, stereoselective pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Serves as a versatile precursor for catalysts, ligands, and specialty chemicals requiring a defined cyclohexene core.
• Academic & R&D: A valuable tool for methodological studies in asymmetric synthesis, total synthesis of natural products, and organocatalysis.
• Material Science: Potential monomer or modifier for creating polymers with specific optical or mechanical properties derived from its rigid, functionalized structure.

Basic Information

Product Name	(3R,4S,5R)-Butyl 3,4,5-Trihydroxycyclohex-1-Enecarboxylate
CAS No.	1246620-91-6
Molecular Formula	C11H18O5
Molecular Weight	230.26 g/mol
Synonyms	Butyl (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-ene-1-carboxylate; (1R,2S,3R)-1-Butoxycarbonyl-2,3,4-trihydroxycyclohex-5-ene; 3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic Acid Butyl Ester (stereospecific); Cyclohex-1-ene-1-carboxylic acid, 3,4,5-trihydroxy-, butyl ester, (3R,4S,5R)-; Chiral Cyclohexene Ester; BTHC Ester
EINECS	Contact for details

Quality Control

Our (3R,4S,5R)-Butyl 3,4,5-Trihydroxycyclohex-1-Enecarboxylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.