Description

2-Bromo-1H-Pyrrolo[3,2-B]Pyridine is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging its heterocyclic core.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a molecular probe or a tagging reagent in bioconjugation and proteomics research.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	2-Bromo-1H-Pyrrolo[3,2-B]Pyridine
CAS No.	1246554-16-4
Molecular Formula	C7H5BrN2
Molecular Weight	197.03 g/mol
Synonyms	2-Bromo-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 2-bromo-; 2-Bromo-7-azaindole; 2-Bromo-1H-7-azaindole; 2-Bromopyrrolo[3,2-b]pyridine; 2-Bromo-1H-pyrrolo[3,2-b]pyridine; 2-Bromo-7-aza-indole; 2-Bromo-1H-7-aza-indole
EINECS	Contact for details

Quality Control

Our 2-Bromo-1H-Pyrrolo[3,2-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder/crystals
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.