Description

6,9-Diazaspiro[4.5]Decan-7-One is a high-value, nitrogen-containing spirocyclic organic compound with the CAS number 1246396-45-1. This heterocyclic building block is of significant interest in advanced pharmaceutical research and fine chemical synthesis due to its unique, rigid three-dimensional structure. It is primarily utilized by medicinal chemists and process development scientists working in drug discovery and development.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Building Block: Used to introduce conformational restraint and improve the pharmacokinetic properties of drug candidates during lead optimization.
• Ligand Synthesis: Employed in the development of specialized ligands for catalysis and receptor binding studies.
• Agrochemical Research: Acts as a key intermediate in the discovery of new herbicides and fungicides with novel modes of action.
• Academic & Contract Research: Utilized in universities and CROs for fundamental research in organic methodology and heterocyclic chemistry.

Basic Information

Product Name	6,9-Diazaspiro[4.5]Decan-7-One
CAS No.	1246396-45-1
Molecular Formula	C8H12N2O
Molecular Weight	152.20 g/mol
Synonyms	6,9-Diazaspiro[4.5]decan-7-one; 7-Oxo-6,9-diazaspiro[4.5]decane; 1,4-Diazaspiro[4.5]decan-2-one (tautomer); Spirocyclic lactam; 2-Oxo-1,4-diazaspiro[4.5]decane; 6,9-Diazaspiro[4.5]decan-7-one, 9CI; A-867744 (potential research code)
EINECS	Contact for details

Quality Control

Our 6,9-Diazaspiro[4.5]Decan-7-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.