Description

n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Galactosyl-1-1'-D-Erythro-Sphingosine is a sophisticated fluorescently labeled sphingolipid derivative, designed for advanced research and diagnostic applications. This compound is critical for studying lipid metabolism, membrane dynamics, and cellular signaling pathways due to its specific galactosyl head group and the bright, photostable BODIPY fluorophore. It is primarily utilized by researchers and developers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on lipidomics, cell biology, and the development of fluorescent probes.

Application

• Fluorescent Labeling of Sphingolipids: Used as a high-fidelity tracer to visualize the localization, trafficking, and metabolism of galactosylceramides and related sphingolipids in live and fixed cells.
• Lipid Raft and Membrane Dynamics Studies: Employed to investigate the organization and fluidity of cell membranes, particularly in lipid raft microdomains, due to its lipophilic nature.
• Metabolic Pathway Analysis: A vital tool in lipidomics for tracking enzymatic activity and metabolic flux in the sphingolipid biosynthesis and degradation pathways.
• Development of Diagnostic Probes: Serves as a key intermediate or active component in creating sensitive assays and probes for detecting specific enzymes or cellular states related to lipid disorders.
• High-Content Screening (HCS): Utilized in automated imaging platforms within drug discovery to identify compounds that modulate sphingolipid-related processes.
• Neuroscience and Myelin Research: Applied in studies of myelination, demyelinating diseases, and neuronal cell biology, given the importance of galactosylceramide in myelin sheath structure.

Basic Information

Product Name	n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Galactosyl-1-1'-D-Erythro-Sphingosine
CAS No.	1246355-61-2
Molecular Formula	C46H73BF2N2O8
Molecular Weight	831.90 g/mol
Synonyms	BODIPY FL C12-Galactosylceramide; GalCer(BODIPY FL C12); BODIPY® FL C12-Galactosylceramide; Fluorescent Galactocerebroside; BODIPY FL-labeled Galactosylsphingosine; n-[11-(4,4-Difluoro-4-bora-3a,4a-diaza-s-indacen-8-yl)undecanoyl]-D-galactosyl-1-1'-D-erythro-sphingosine; Galactocerebroside BODIPY FL C12 analog; BODIPY-GalCer
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and fluorescent performance. A comprehensive Certificate of Analysis (COA) detailing assay purity, impurity profile, and spectral properties is provided with every shipment to ensure traceability and support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is both light-sensitive and hygroscopic. For long-term stability, store as supplied in the original sealed container. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Excitation/Emission Maxima	~503 nm / ~512 nm (in suitable solvent)
Solubility	Soluble in DMSO, DMF, ethanol; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.