Description

5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine-4-Carbaldehyde is a high-value halogenated heterocyclic building block with a reactive aldehyde functional group. This compound is critical for medicinal chemistry and pharmaceutical research, serving as a versatile intermediate in the synthesis of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel drug candidates and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides and fungicides.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and target engagement.
• Material Science: Potential precursor for organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific advanced intermediates.

Basic Information

Product Name	5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine-4-Carbaldehyde
CAS No.	1246088-64-1
Molecular Formula	C8H4ClIN2O
Molecular Weight	306.49 g/mol
Synonyms	5-Chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 5-chloro-6-iodo-1H-pyrrolo[2,3-b]-; 1H-Pyrrolo[2,3-b]pyridine-4-carbaldehyde, 5-chloro-6-iodo-; 5-Chloro-6-iodo-4-formyl-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde; 1246088-64-1
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine-4-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.