Description

5-Bromo-2-Ethyl-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for medicinal chemistry research and pharmaceutical development, offering a versatile scaffold for creating novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex molecules targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical space.
• Agrochemical Development: Employed in the research and synthesis of novel active ingredients for crop protection products.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential use in the development of organic electronic materials and advanced polymers due to its complex aromatic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process scale-up projects.

Basic Information

Product Name	5-Bromo-2-Ethyl-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1246088-48-1
Molecular Formula	C₁₇H₁₄BrIN₂O₂S
Molecular Weight	517.18 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine, 5-bromo-2-ethyl-3-iodo-1-(phenylsulfonyl)-; 5-Bromo-2-ethyl-3-iodo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1246088-48-1; 5-Br-2-Et-3-I-1-PhSO2-Pyrrolo[2,3-b]Pyridine; Bromo-Ethyl-Iodo-Phenylsulfonyl Pyrrolopyridine; Pyrrolopyridine Sulfonamide Derivative
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Ethyl-3-Iodo-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.