Description

2-Boc-2,5-Diazaspiro[3.5]Nonane is a high-value, protected spirocyclic diamine building block essential for advanced organic synthesis. Its rigid, three-dimensional structure and dual nitrogen functionality make it a critical intermediate for constructing complex molecular architectures with enhanced pharmacological properties. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel drug candidates, particularly in the areas of central nervous system (CNS) therapeutics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of bioactive molecules targeting GPCRs, kinases, and other therapeutic proteins.
• Proteolysis Targeting Chimera (PROTAC) Development: Used as a linker or core component to create bifunctional molecules for targeted protein degradation.
• CNS Drug Discovery: Employed in constructing spirocyclic analogs for potential treatments of neurological disorders.
• Agrochemical Research: Serves as a building block for novel active ingredients with unique modes of action.
• Ligand and Catalyst Design: Utilized in creating novel chelating agents and chiral auxiliaries for asymmetric synthesis.
• Peptidomimetics: Incorporated to introduce conformational restraint and improve metabolic stability in peptide-based drug design.

Basic Information

Product Name	2-Boc-2,5-Diazaspiro[3.5]Nonane
CAS No.	1246034-93-4
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	tert-Butyl 2,5-diazaspiro[3.5]nonane-2-carboxylate; 2,5-Diazaspiro[3.5]nonane-2-carboxylic acid, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-2,5-diazaspiro[3.5]nonane; 2-Boc-2,5-diazaspiro[3.5]nonane; Boc-Protected 2,5-Diazaspiro[3.5]nonane; 2,5-Diazaspiro[3.5]nonane, Boc-protected; 2-N-Boc-2,5-diazaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Every batch of 2-Boc-2,5-Diazaspiro[3.5]Nonane is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes HPLC purity ≥98% and full characterization by NMR, MS, and IR spectroscopy. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.