Description

tert-Butyl 2-(3-Bromophenyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with a brominated aromatic substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel drug candidates, particularly in the areas of central nervous system (CNS) and oncology therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Library Synthesis for High-Throughput Screening: Used to create focused chemical libraries for screening against novel biological targets.

Basic Information

Product Name	tert-Butyl 2-(3-Bromophenyl)Piperidine-1-Carboxylate
CAS No.	1246034-77-4
Molecular Formula	C16H22BrNO2
Molecular Weight	340.26 g/mol
Synonyms	1-Boc-2-(3-bromophenyl)piperidine; 2-(3-Bromophenyl)-1-(tert-butoxycarbonyl)piperidine; 1-(tert-Butoxycarbonyl)-2-(3-bromophenyl)piperidine; tert-Butyl 2-(3-bromophenyl)-1-piperidinecarboxylate; 2-(3-Bromophenyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-2-(3-bromophenyl)piperidine; 1246034-77-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(3-Bromophenyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.