Description

(2-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Methanamine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a versatile intermediate for introducing specific pharmacophores and modifying physicochemical properties in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine-tune product performance.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands in transition metal catalysis and organocatalysis, enabling more efficient synthetic routes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom synthesis services and discovery chemistry programs in biotechnology and specialty chemical companies.

Basic Information

Product Name	(2-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Methanamine
CAS No.	1245916-03-3
Molecular Formula	C7H6ClF3N2
Molecular Weight	210.58 g/mol
Synonyms	3-(Aminomethyl)-2-chloro-5-(trifluoromethyl)pyridine; 2-Chloro-5-(trifluoromethyl)-3-pyridinemethanamine; 1-[2-Chloro-5-(trifluoromethyl)pyridin-3-yl]methanamine; (2-Chloro-5-(trifluoromethyl)-3-pyridyl)methanamine; 3-Pyridinemethanamine, 2-chloro-5-(trifluoromethyl)-; 2-Chloro-5-trifluoromethyl-pyridin-3-ylmethylamine
EINECS	Contact for details

Quality Control

Our (2-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.