Description

1H-Pyrrolo[2,3-C]Pyridine, 2,3-Dihydro-5-(Trifluoromethyl)- is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to introduce the trifluoromethyl group into complex molecular architectures, a modification known to dramatically enhance metabolic stability, lipophilicity, and binding affinity in active pharmaceutical ingredients. It is a critical intermediate for research and development chemists in the pharmaceutical and agrochemical industries, enabling the creation of novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Serves as a precursor for specialty chemicals and advanced organic electronic materials.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs to improve drug-like properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridine, 2,3-Dihydro-5-(Trifluoromethyl)-
CAS No.	1245914-66-2
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	5-(Trifluoromethyl)-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine; 2,3-Dihydro-5-(trifluoromethyl)-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine, 2,3-dihydro-5-(trifluoromethyl)-; 5-Trifluoromethyl-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine; Fluorinated pyrrolopyridine building block; Trifluoromethyl DHPP intermediate
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-C]Pyridine, 2,3-Dihydro-5-(Trifluoromethyl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is fully characterized and analyzed using advanced techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.