Description

2-Oxa-6-Azaspiro[3.4]Octane-6-Carboxylic Acid tert-Butyl Ester is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and improve drug-like properties.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for potential APIs.
• Spirocyclic Compound Library Synthesis: Essential for creating diverse libraries of spirocyclic compounds for high-throughput screening in drug discovery programs.
• Chemical Biology Probes: Can be incorporated into molecular probes to study biological pathways and protein function.

Basic Information

Product Name	2-Oxa-6-Azaspiro[3.4]Octane-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1245816-31-2
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	tert-Butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate; 6-(tert-Butoxycarbonyl)-2-oxa-6-azaspiro[3.4]octane; 2-Oxa-6-azaspiro[3.4]octane-6-carboxylic acid, 1,1-dimethylethyl ester; Boc-2-oxa-6-azaspiro[3.4]octane; Spirocyclic Boc-protected amine ether
EINECS	Contact for details

Quality Control

Every batch of 2-Oxa-6-Azaspiro[3.4]Octane-6-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.