Description

2-Oxa-6-Azaspiro[3,5]Nonane-6-Carboxylic Acid tert-Butyl Ester is a high-value, spirocyclic building block and protected amino acid derivative essential for advanced organic synthesis. Its unique rigid bicyclic structure and orthogonal protecting groups make it a critical intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors, CNS-active compounds, and other therapeutics requiring constrained peptide mimetics.
• Agrochemical Research: Used in the design and synthesis of new generation pesticides and herbicides, where its spirocyclic scaffold can contribute to improved biological activity and stability.
• Peptidomimetics & Constrained Analogs: Serves as a versatile scaffold for creating conformationally restricted peptide analogs to enhance metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new chemical space in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Oxa-6-Azaspiro[3,5]Nonane-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1245816-29-8
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	tert-Butyl 2-oxa-6-azaspiro[3.5]nonane-6-carboxylate; 6-(tert-Butoxycarbonyl)-2-oxa-6-azaspiro[3.5]nonane; 2-Oxa-6-azaspiro[3.5]nonane-6-carboxylic acid, 1,1-dimethylethyl ester; Boc-2-oxa-6-azaspiro[3.5]nonane; Spirocyclic Boc-protected amino ester
EINECS	Contact for details

Quality Control

Our production of 2-Oxa-6-Azaspiro[3,5]Nonane-6-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.