Description

3-Bromo-5-Chloro-1H-Pyrazolo[3,4-B]Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds to study biological processes and protein function.
• Material Science: Potential building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production for client projects.

Basic Information

Product Name	3-Bromo-5-Chloro-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1245649-96-0
Molecular Formula	C6H3BrClN3
Molecular Weight	232.47 g/mol
Synonyms	3-Bromo-5-chloro-1H-pyrazolo[3,4-b]pyridine; 5-Chloro-3-bromo-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-bromo-5-chloro-; 1245649-96-0; 3-Br-5-Cl-1H-pyrazolo[3,4-b]pyridine; 5-Chloro-3-bromo-7-azaindole (common name); 3-Bromo-5-chloro-7-azaindole; 3-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine (isomeric name check).
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment supports cGMP and ISO-guided production for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.