Description

2-(Benzyloxy)-5-(2,2,2-trifluoroethyl)pyridine is a high-value, fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring a benzyl-protected oxygen and a trifluoroethyl side chain, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at pharmaceutical R&D and fine chemical manufacturers engaged in developing novel active ingredients, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoroethyl group can improve metabolic stability and lipophilicity.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and fluorinated polymers.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological mechanisms and diagnostic applications.

Basic Information

Product Name	2-(Benzyloxy)-5-(2,2,2-Trifluoroethyl)Pyridine
CAS No.	1245646-58-5
Molecular Formula	C14H12F3NO
Molecular Weight	267.25 g/mol
Synonyms	5-(2,2,2-Trifluoroethyl)-2-(phenylmethoxy)pyridine; 2-Benzyloxy-5-(2,2,2-trifluoroethyl)pyridine; 2-(Benzyloxy)-5-(trifluoroethyl)pyridine; Pyridine, 2-(benzyloxy)-5-(2,2,2-trifluoroethyl)-; 1245646-58-5
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-5-(2,2,2-trifluoroethyl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.