Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-5-Nitro-1-(Phenylsulfonyl)- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates a halogen, a nitro group, and a sulfonyl-protected nitrogen, making it a versatile intermediate for constructing complex pharmacophores. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its fused pyrrolopyridine scaffold.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical spaces.
• Custom Synthesis: A starting material for the contract manufacturing of complex, proprietary molecules for client-specific applications.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-5-Nitro-1-(Phenylsulfonyl)-
CAS No.	1245646-53-0
Molecular Formula	C13H8BrN3O4S
Molecular Weight	382.19 g/mol
Synonyms	4-Bromo-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-4-bromo-5-nitro-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-5-nitro-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common alias); 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-5-nitro-1-(phenylsulfonyl)-; 1245646-53-0; 4-Br-5-NO2-1-Phenylsulfonyl-pyrrolo[2,3-b]pyridine; Bromo-nitrophenylsulfonyl pyrrolopyridine; Pyrrolopyridine sulfonamide intermediate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-5-Nitro-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable performance in your most sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.