Description

tert-Butyl 4-Hydroxy-2-oxopiperidine-1-carboxylate is a high-purity, protected piperidinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular scaffolds, particularly in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing piperidine or piperidinone pharmacophores.
• Organic Synthesis Reagent: Used in multi-step synthesis for constructing heterocyclic compounds and introducing protected functional groups.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides where specific nitrogen-containing heterocycles are required.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for creating compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, dyes, and advanced materials requiring precise molecular architecture.

Basic Information

Product Name	tert-Butyl 4-Hydroxy-2-oxopiperidine-1-carboxylate
CAS No.	1245646-10-9
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	1-Boc-4-hydroxy-2-piperidinone; 4-Hydroxy-1-(tert-butoxycarbonyl)-2-piperidinone; tert-Butyl 4-hydroxy-2-oxo-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-hydroxy-2-piperidinone; 4-Hydroxy-2-oxopiperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-hydroxypiperidin-2-one; Boc-4-hydroxy-2-piperidinone
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Hydroxy-2-oxopiperidine-1-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) documenting all specifications are available upon request, supporting compliance with cGMP and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.