Description

4-Chloro-5-Nitro-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused pyrrolopyridine core, functionalized with chloro and nitro groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active small molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Employed as a probe or a tag in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-5-Nitro-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1245645-97-9
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	4-Chloro-5-nitropyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-nitro-; 4-Chloro-5-nitro-7-azaindole; 4-Chloro-5-nitro-1H-pyrrolo[2,3-b]pyridine; 5-Nitro-4-chloro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-5-nitro-1H-7-azaindole
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Nitro-1H-Pyrrolo[2,3-B]Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA), including purity (HPLC), identity confirmation (NMR, MS), and impurity profile, is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder/crystals
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.