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7-Fluoro-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine CAS NO 1245645-49-1


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CAS No.:1245645-49-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Fluoro-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine is a high-value, heterocyclic organic compound featuring a fused triazolopyridine core with a fluorine substituent and an amine functional group. This unique structure makes it a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
  • Medicinal Chemistry Building Block: Used extensively in drug discovery for scaffold hopping, lead optimization, and creating targeted compound libraries due to its fluorine atom and reactive amine group.
  • Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the triazolopyridine moiety.
  • Material Science Precursor: Potential use in the synthesis of organic electronic materials, ligands for catalysis, and advanced polymers.
  • Chemical Biology Probe: Utilized in biochemical research to develop enzyme inhibitors or molecular probes for studying biological pathways.

Basic Information

Product Name 7-Fluoro-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine
CAS No. 1245645-49-1
Molecular Formula C6H5FN4
Molecular Weight 152.13 g/mol
Synonyms 7-Fluoro-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 7-Fluoro-1,2,4-triazolo[1,5-a]pyridin-2-amine; 2-Amino-7-fluoro-[1,2,4]triazolo[1,5-a]pyridine; 7-Fluoro-1,2,4-triazolo[1,5-a]pyridin-2-ylamine; 1245645-49-1; 7-Fluoro-1,2,4-triazolo[1,5-a]pyridin-2-amine (ACI); FTAP Amine
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Quality Control

Our 7-Fluoro-[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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