Description

1-(2-Chloropyridin-4-Yl)Ethanol is a versatile pyridine-based chiral building block and intermediate of significant importance in modern synthetic chemistry. Its core value lies in providing a functionalized scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chloropyridine and ethanol functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the chloropyridine moiety is critical for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional organic materials, including liquid crystals and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(2-Chloropyridin-4-Yl)Ethanol
CAS No.	1245644-98-7
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	4-(1-Hydroxyethyl)-2-chloropyridine; 2-Chloro-4-(1-hydroxyethyl)pyridine; 1-(2-Chloro-4-pyridinyl)ethanol; α-(2-Chloro-4-pyridyl)ethanol; (2-Chloropyridin-4-yl)methanol, methyl-; 2-Chloro-4-(α-hydroxyethyl)pyridine; 1-(2-Chloro-4-pyridyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 1-(2-Chloropyridin-4-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting its use in GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.