Description

3-((Naphthalen-6-Yl)Methoxy)-5-Bromopyridine is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound matters for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated pyridine core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating organic electronic materials, such as OLEDs or conductive polymers.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	3-((Naphthalen-6-Yl)Methoxy)-5-Bromopyridine
CAS No.	1245644-34-1
Molecular Formula	C₁₆H₁₂BrNO
Molecular Weight	314.18 g/mol
Synonyms	5-Bromo-3-[(naphthalen-6-yl)methoxy]pyridine; 3-[(6-Naphthyl)methoxy]-5-bromopyridine; 5-Bromo-3-((6-naphthyl)methoxy)pyridine; 3-(Naphthalen-6-ylmethoxy)-5-bromopyridine; 5-Bromo-3-(naphthalen-6-ylmethoxy)pyridine; 1245644-34-1; 3-(6-Naphthylmethoxy)-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 3-((Naphthalen-6-Yl)Methoxy)-5-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.