Description

(S)-Methyl 3-Amino-3-(o-Tolyl)Propanoate Hcl CAS NO 1245606-66-9 is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates. Its value lies in its defined stereochemistry and functional groups, which enable precise molecular construction in asymmetric synthesis. This compound is primarily needed by research institutions and pharmaceutical companies engaged in developing new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents.
• Asymmetric Synthesis: Used in the construction of complex molecules requiring high enantiomeric purity for drug discovery programs.
• Peptidomimetic Research: Serves as a precursor for non-natural amino acid derivatives used in peptide-based drug design.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds for studying biological pathways and target engagement.
• Catalyst Ligand Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Process Chemistry: Employed in scale-up and route optimization for the commercial production of advanced pharmaceutical intermediates.

Basic Information

Product Name	(S)-Methyl 3-Amino-3-(o-Tolyl)Propanoate Hydrochloride
CAS No.	1245606-66-9
Molecular Formula	C11H15NO2 • HCl
Molecular Weight	229.70 g/mol
Synonyms	(S)-Methyl 3-amino-3-(2-methylphenyl)propanoate hydrochloride; Methyl (3S)-3-amino-3-(2-methylphenyl)propanoate hydrochloride; (S)-3-Amino-3-(o-tolyl)propionic acid methyl ester hydrochloride; (S)-Methyl 3-amino-3-(2-tolyl)propionate HCl; (S)-Methyl 3-amino-3-(2-methylphenyl)propionate hydrochloride; (S)-3-Amino-3-(2-methylphenyl)propanoic acid methyl ester hydrochloride; (S)-Methyl 3-amino-3-(o-tolyl)propanoate HCl
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. We adhere to strict quality management protocols suitable for GMP and ICH guidelines, ensuring batch-to-batch consistency and traceability for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.