Description

Dimethyl 2-(5-Bromo-3-Nitropyridin-2-Yl)Malonate is a high-purity, multi-functional chemical building block designed for advanced organic synthesis. This compound is valued for its reactive bromo and nitro substituents on the pyridine ring, which enable precise and versatile derivatization in complex molecular construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Dimethyl 2-(5-Bromo-3-Nitropyridin-2-Yl)Malonate
CAS No.	1245563-09-0
Molecular Formula	C11H9BrN2O6
Molecular Weight	345.11 g/mol
Synonyms	Dimethyl (5-Bromo-3-nitropyridin-2-yl)malonate; 2-(5-Bromo-3-nitropyridin-2-yl)malonic acid dimethyl ester; Propanedioic acid, 2-(5-bromo-3-nitro-2-pyridinyl)-, 1,3-dimethyl ester; 5-Bromo-3-nitro-2-pyridylmalonic acid dimethyl ester; 1,3-Dimethyl 2-(5-bromo-3-nitropyridin-2-yl)propanedioate
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(5-Bromo-3-Nitropyridin-2-Yl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical specifications. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.