Description

3-Bromo-5-Iodo-4-Methylpyridine is a high-value halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in cross-coupling reactions and as a precursor to novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides with specific modes of action.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Negishi coupling reactions to form biaryl and heterobiaryl structures.
• Chemical Biology Probes: Used to create tagged molecules for studying biological processes and target engagement.

Basic Information

Product Name	3-Bromo-5-Iodo-4-Methylpyridine
CAS No.	1245536-23-5
Molecular Formula	C6H5BrIN
Molecular Weight	297.92 g/mol
Synonyms	4-Methyl-3-bromo-5-iodopyridine; 3-Bromo-5-iodo-4-picoline; 5-Iodo-3-bromo-4-methylpyridine; Pyridine, 3-bromo-5-iodo-4-methyl-; 4-Methyl-3,5-dihalopyridine (mixed halogen); 3-Br-5-I-4-MePy
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Iodo-4-Methylpyridine is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support development from discovery through to scale-up, meeting the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.