Description

6-Bromospiro[3H-Indene-2,4'-Cyclohexane]-1,1'-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating new therapeutic agents and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its brominated spiro scaffold for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential electron-transport or host material in the fabrication of OLED devices due to its rigid, conjugated structure.
• Ligand & Catalyst Development: Provides a versatile framework for constructing complex chelating ligands in asymmetric catalysis and transition metal complexes.
• Academic & Industrial R&D: Employed in methodological studies and discovery chemistry for constructing spirocyclic and polycyclic compounds.
• Material Science: Investigated as a monomer or cross-linking agent for high-performance polymers with specific thermal and optical properties.

Basic Information

Product Name	6-Bromospiro[3H-Indene-2,4'-Cyclohexane]-1,1'-Dione
CAS No.	1245514-96-8
Molecular Formula	C14H13BrO2
Molecular Weight	293.16 g/mol
Synonyms	6-Bromo-1'H-spiro[cyclohexane-1,2'-indene]-1',3'-dione; 6-Bromospiro[cyclohexane-1,2'-indene]-1',3'(3'H)-dione; 6-Bromo-1'H-spiro[cyclohexane-1,2'-inden]-1',3'-dione; 6-Bromospiro[indene-2,4'-cyclohexane]-1,1'-dione; 6-Bromospiro[3H-indene-2,4'-cyclohexane]-1,1'-dione; 1245514-96-8; Spiro[3H-indene-2,4'-cyclohexane]-1,1'-dione, 6-bromo-
EINECS	Contact for details

Quality Control

Our 6-Bromospiro[3H-Indene-2,4'-Cyclohexane]-1,1'-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and advanced synthesis. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.