Description

[2-(9H-Fluoren-2-Yldimethylsilyl)Phenyl]Methanol is a specialized organosilicon building block featuring a fluorenyl-protected silyl group and a benzylic alcohol functionality. This compound is critical for advanced organic synthesis, particularly in the development of novel materials and complex molecular architectures where precise steric and electronic control is required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as ligand synthesis, polymer modification, and as a key intermediate in cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those requiring fluorene-based scaffolds.
• Ligand Precursor for Catalysis: Used to develop novel ligands for transition metal catalysts in asymmetric synthesis and cross-coupling reactions (e.g., Suzuki, Heck).
• Advanced Material Synthesis: A building block for creating functionalized polymers, dendrimers, and organic electronic materials due to its fluorenyl group's optoelectronic properties.
• Agrochemical Research: Employed in the research and development of new crop protection agents and plant growth regulators.
• Surface Modification Agent: Can be used to functionalize silicon-based surfaces or nanoparticles via its reactive silyl and alcohol groups.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	[2-(9H-Fluoren-2-Yldimethylsilyl)Phenyl]Methanol
CAS No.	1244855-58-0
Molecular Formula	C22H22OSi
Molecular Weight	330.50 g/mol
Synonyms	(2-((9H-Fluoren-2-yl)dimethylsilyl)phenyl)methanol; 2-((9H-Fluoren-2-yl)dimethylsilyl)benzenemethanol; Fluoren-2-yldimethylsilylbenzyl Alcohol; (2-(Fluoren-2-yldimethylsilyl)phenyl)methanol; [2-(9H-Fluoren-2-yldimethylsilyl)phenyl]methanol; Fluorenyldimethylsilyl Benzyl Alcohol Derivative
EINECS	Contact for details

Quality Control

Our [2-(9H-Fluoren-2-Yldimethylsilyl)Phenyl]Methanol is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profile. We support our clients' regulatory needs and ensure our products meet the stringent requirements for advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.