Description

2-Cyclopropylnicotinic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1244761-65-6. This compound is a critical building block in modern medicinal chemistry, valued for its unique cyclopropyl-substituted nicotinic acid scaffold which is instrumental in modulating the biological activity of target molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective therapies.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• CNS Drug Development: Serves as a core scaffold for compounds targeting neurological disorders.
• Agrochemical Synthesis: Potential intermediate in the development of new generation pesticides and herbicides.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalytic and material science applications.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory chemical synthesis.

Basic Information

Product Name	2-Cyclopropylnicotinic Acid
CAS No.	1244761-65-6
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	2-Cyclopropylpyridine-3-carboxylic Acid; Nicotinic acid, 2-cyclopropyl-; 3-Pyridinecarboxylic acid, 2-cyclopropyl-; 2-Cyclopropyl-3-pyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylnicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.