Description

Methyl 3-Bromo-4,5-Difluorobenzoate is a high-purity, multi-functional aromatic ester building block essential for advanced organic synthesis. This compound matters because its unique halogenated structure provides specific reactivity for constructing complex molecules with precision. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, where the difluoro and bromo substituents contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, halogenated benzoic acid derivatives.

Basic Information

Product Name	Methyl 3-Bromo-4,5-Difluorobenzoate
CAS No.	1244642-70-3
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	3-Bromo-4,5-difluorobenzoic acid methyl ester; Methyl 3-bromo-4,5-difluorobenzoate; Benzoic acid, 3-bromo-4,5-difluoro-, methyl ester; 4,5-Difluoro-3-bromobenzoic acid methyl ester; Methyl 4,5-difluoro-3-bromobenzoate; 3-Bromo-4,5-difluorobenzoic acid, methyl ester; Methyl ester of 3-bromo-4,5-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-4,5-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.