Description

Azido-Peg6-Azide is a heterobifunctional polyethylene glycol (PEG) linker featuring terminal azide groups, widely used in click chemistry applications. Its core value lies in its role as a versatile spacer and crosslinker for the bio-conjugation of molecules, enabling the formation of stable triazole linkages under mild conditions. This product is essential for researchers and manufacturers in pharmaceutical development, bioconjugation, materials science, and proteomics who require reliable, high-purity linkers for constructing complex molecular architectures.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used as a linker to attach cytotoxic drugs, fluorescent dyes, or other payloads to antibodies, proteins, or peptides.
• Polymer and Materials Science: Serves as a crosslinking agent or functional modifier in the synthesis of hydrogels, smart materials, and surface coatings via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Proteomics and Biomarker Discovery: Facilitates the labeling and enrichment of biomolecules for mass spectrometry analysis and activity-based protein profiling.
• Diagnostic Reagent Formulation: Employed in the development of diagnostic assays and imaging probes by linking targeting moieties to signal-generating molecules.
• Nanoparticle Functionalization: Used to modify the surface of nanoparticles (e.g., liposomes, dendrimers, quantum dots) for targeted drug delivery and imaging.
• Solid-Phase Peptide Synthesis (SPPS): Acts as a handle for the site-specific modification of peptides during or after synthesis.
• DNA/RNA Labeling: Enables the introduction of azide groups into oligonucleotides for subsequent conjugation with alkyne-modified tags.
• Chemical Biology Tool Development: A key reagent for creating chemical probes to study biological processes and pathways.

Basic Information

Item	Details
Product Name	Azido-Peg6-Azide
CAS No.	1243536-56-2
Molecular Formula	C18H34N6O8
Molecular Weight	462.50 g/mol
Synonyms	1,11-Bis-azido-3,6,9-trioxaundecane; 3,6,9,12,15,18-Hexaoxahenicosane-1,21-diyl diazide; Azido-PEG6-azide; N3-PEG6-N3; Bis-azido-PEG6; PEG6-diazide; 1-Azido-11-azido-3,6,9-trioxaundecane; Diaza-15-crown-5 derivative (azido-terminated)
EINECS	Contact for details

Quality Control

Our Azido-Peg6-Azide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system adheres to ISO 9001 standards, and we support compliance with REACH regulations for the global market.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (e.g., argon or nitrogen) in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.