Description

2-Bromo-4-Cyclopropoxypyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated pyridine core substituted with a cyclopropoxy group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for applications in oncology and central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents and pesticides.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Precursor: Potential building block for creating functionalized polymers or organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-Bromo-4-Cyclopropoxypyridine
CAS No.	1243394-76-4
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	4-Cyclopropoxy-2-bromopyridine; 2-Bromo-4-(cyclopropyloxy)pyridine; Pyridine, 2-bromo-4-cyclopropoxy-; 1243394-76-4; 2-Bromo-4-cyclopropyloxypyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Cyclopropoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.