Description

6-Bromo-3-cyclopropoxy-2-methoxypyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a bromine substituent and a cyclopropoxy ether linkage on the pyridine core, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, CNS-active compounds, and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to its halogenated pyridine structure.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, where its electron-deficient pyridine ring is beneficial.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for use in client-specific projects requiring bespoke chemical entities.

Basic Information

Product Name	6-Bromo-3-cyclopropoxy-2-methoxypyridine
CAS No.	1243344-95-7
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	2-Methoxy-6-bromo-3-cyclopropoxypyridine; 3-Cyclopropoxy-2-methoxy-6-bromopyridine; 6-Bromo-2-methoxy-3-cyclopropoxypyridine; 6-Bromo-3-(cyclopropyloxy)-2-methoxypyridine; Pyridine, 6-bromo-3-cyclopropoxy-2-methoxy-; (6-Bromo-2-methoxypyridin-3-yloxy)cyclopropane
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-cyclopropoxy-2-methoxypyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.