Description

Methyl 2-(2-Bromophenyl)-3-Oxobutanoate is a specialized brominated keto ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the construction of complex heterocyclic and pharmaceutical intermediates. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as palladium-catalyzed cross-coupling reactions and the synthesis of biologically active molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing a bromophenyl moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to form new carbon-carbon bonds.
• Academic & Contract Research: A valuable reagent for methodological studies and the exploration of new synthetic pathways in university and CRO laboratories.

Basic Information

Product Name	Methyl 2-(2-Bromophenyl)-3-Oxobutanoate
CAS No.	1243144-97-9
Molecular Formula	C11H11BrO3
Molecular Weight	271.11 g/mol
Synonyms	Methyl 2-(2-bromophenyl)-3-oxobutanoate; 3-Oxobutanoic acid, 2-(2-bromophenyl)-, methyl ester; Methyl (2-bromobenzoyl)acetate; 2-(2-Bromophenyl)-3-oxobutanoic acid methyl ester; Methyl 2-bromobenzoylacetate; 2-Bromophenyl methyl acetoacetate; Methyl α-(2-bromobenzoyl)acetate; Methyl 3-oxo-2-(2-bromophenyl)butanoate
EINECS	Contact for details

Quality Control

Our Methyl 2-(2-Bromophenyl)-3-Oxobutanoate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.