Description

4,4-Difluoro-8-(4-(3-Azidopropoxy))Phenyl-1,3,5,7-Tetramethyl-4-Bora-3A,4 A-Diaza-S-Indacene is a highly specialized, functionalized BODIPY (boron-dipyrromethene) dye derivative, distinguished by its reactive azide group. This compound matters for its unique ability to participate in bioorthogonal "click chemistry" reactions, such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling precise labeling and conjugation in complex systems. It is primarily needed by researchers and developers in the life sciences, pharmaceutical, and advanced materials sectors for applications in fluorescence labeling, bioimaging, molecular probes, and polymer modification.

Application

• Bioorthogonal Labeling & Conjugation: Utilized as a fluorescent tag for proteins, antibodies, nucleic acids, and other biomolecules via click chemistry.
• Live-Cell & Super-Resolution Imaging: Serves as a photostable fluorescent probe for tracking cellular processes, organelle labeling, and advanced microscopy techniques.
• Chemical Biology & Proteomics: Enables activity-based protein profiling (ABPP) and the study of protein function and interactions in their native environment.
• Polymer & Materials Science: Used to functionalize surfaces, nanoparticles, hydrogels, and polymers with fluorescent properties for sensing and diagnostic applications.
• Diagnostic Assay Development: Incorporated into lateral flow assays, ELISA, and other diagnostic platforms for high-sensitivity detection.
• Flow Cytometry & Fluorescence-Activated Cell Sorting (FACS): Acts as a bright and stable fluorophore for cell surface marker staining and analysis.
• Drug Delivery & Theranostics: Facilitates the tracking of drug carriers, liposomes, and therapeutic conjugates in vitro and in vivo.
• Academic & Industrial Research: A key reagent for developing novel fluorescent tools and exploring new applications in photonics and nanotechnology.

Basic Information

Product Name	4,4-Difluoro-8-(4-(3-Azidopropoxy))Phenyl-1,3,5,7-Tetramethyl-4-Bora-3A,4 A-Diaza-S-Indacene
CAS No.	1242274-58-3
Molecular Formula	C24H25BF2N6O
Molecular Weight	462.31 g/mol
Synonyms	BODIPY FL Azide; 3-Azidopropyl BODIPY FL; 4,4-Difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-propionic acid, 3-azidopropyl ester; Azide-PEG3-BODIPY FL; BDP FL Azide; BODIPY® FL Azide; 8-(4-(3-Azidopropoxy)phenyl)-1,3,5,7-tetramethyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
EINECS	Contact for details

Quality Control

Our production of this high-value specialty chemical adheres to stringent quality protocols. Each batch undergoes comprehensive analytical characterization, including HPLC purity analysis, NMR spectroscopy, and mass spectrometry to confirm identity, purity, and the integrity of the reactive azide functionality. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant (e.g., in a freezer). The product is light-sensitive and moisture-sensitive. Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation. For long-term storage, keep under an inert atmosphere (argon or nitrogen).

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95% (Area %)
Absorption (λmax)	~504 nm
Emission (λmax)	~511 nm
Extinction Coefficient (ε)	Contact for details
Fluorescence Quantum Yield (φ)	Contact for details
Water Content (KF)	< 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.