Description

Fingolimod Palmitate Amide CAS NO 1242271-26-6 is a high-purity synthetic intermediate, specifically a palmitoylated amide derivative of the active pharmaceutical ingredient Fingolimod. This compound is critical for pharmaceutical research and development, particularly in the synthesis and study of novel prodrug formulations and lipid-conjugated therapeutics. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for developing advanced drug delivery systems and investigating metabolic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for novel Fingolimod analogs and prodrugs.
• Prodrug Development: Serves as a precursor for creating lipid-conjugated prodrugs aimed at enhancing bioavailability and targeted delivery.
• Metabolic Studies: Used in research to investigate the in-vivo hydrolysis and metabolic fate of fatty acid-amidated drug compounds.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in API manufacturing.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for immunomodulatory therapies.
• Process Chemistry: Used in scaling up and optimizing synthetic routes for GMP production of related active pharmaceutical ingredients.

Basic Information

Product Name	Fingolimod Palmitate Amide
CAS No.	1242271-26-6
Molecular Formula	C39H74N2O2
Molecular Weight	602.99 g/mol
Synonyms	2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol palmitamide; FTY720 Palmitamide; Fingolimod Palmitamide; (2-Amino-2-{2-[4-(octyloxy)phenyl]ethyl}propane-1,3-diyl) dipalmitate amide; FTY720-PA; Sphingosine 1-phosphate receptor modulator palmitate amide; N-Palmitoyl-FTY720 amide
EINECS	Contact for details

Quality Control

Our Fingolimod Palmitate Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.