Description

6-Chloro-5-Iodonicotinamide is a high-purity halogenated nicotinamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals engaged in developing new active ingredients, particularly in the fields of drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive nicotinamide core.
• Chemical Synthesis Building Block: The chloro and iodo substituents offer distinct sites for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed processes.
• Material Science Research: Investigated as a monomer or additive for creating functional polymers with specific electronic properties.
• Academic & Institutional R&D: Serves as a standard reagent in university and corporate laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	6-Chloro-5-Iodonicotinamide
CAS No.	1242268-21-8
Molecular Formula	C6H4ClIN2O
Molecular Weight	282.47 g/mol
Synonyms	5-Iodo-6-chloropyridine-3-carboxamide; 3-Carbamoyl-5-iodo-6-chloropyridine; 6-Chloro-5-iodo-3-pyridinecarboxamide; Nicotinamide, 6-chloro-5-iodo-; 6-Chloro-5-iodonicotinamide; 5-Iodo-6-chloronicotinamide; 6-Chloro-5-iodopyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Iodonicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.